Hecog trial study breast cancer

Clinical trials are research studies that involve people. The clinical trials on this list are for breast cancer treatment. All trials on the list are supported by NCI.

Examples: Cancer AND drug name. Pneumonia AND sponsor name. How to search [pdf].

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Researchers confirm the poor quality of care for men affected by breast cancer and urge for a clinical trial. Brussels, 2 February — Recent findings from the International Male Breast Cancer Programme confirm that male and female breast cancers are undeniably different and that 1 out of 3 men affected by the disease is not treated optimally. They also highlight a breast cancer subtype that seems to occur only in men.

In the current study, we performed a complete analysis, with four different methods, of all four HER family receptors, in a series of patients with metastatic breast cancer treated with trastuzumab-based regimens and evaluated their prognostic value. Formalin-fixed paraffin-embedded tumor tissue samples were collected from patients, considered to be HER2-positive when assessed at the local laboratories. Central review of HER2 status by IHC and fluorescence in situ hybridization revealed that of the patients, only

JavaScript is disabled for your browser. Some features of this site may not work without it. Author Pentheroudakis, George Kotoula, V.

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Psyrri, K. Kalogeras, R. Kronenwett, R.

Trastuzumab with a taxane as first-line therapy is now the standard of care for patients with human epidermal growth factor receptor 2 HER-2 -positive metastatic breast cancer MBC. The search for additional and more effective trastuzumab-based therapies continues. Novel combinations of trastuzumab with chemotherapeutic agents, including vinorelbine, gemcitabine, and capecitabine, and hormonal therapy agents, such as tamoxifen and aromatase inhibitors, are currently under investigation in clinical trials.

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Please take this quick survey to tell us about what happens after you publish a paper. Medical Oncology. Patients with metastatic breast cancer receive multiple lines of cytotoxic chemotherapy, with taxane and anthracycline-based regimens being the most active.

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Study record managers: refer to the Data Element Definitions if submitting registration or results information. Drug: Lapatinib Co-administration of lapatinib mg once daily during the WBRT period 2 weeks and then monotherapy with lapatinib mg once daily for 4 weeks. The patients will be followed-up every 12 weeks for disease progression and survival.

Several studies support an important role of angiogenesis in breast cancer growth and metastasis. Formalin-fixed paraffin-embedded tumor tissue samples were collected from early-stage breast cancer patients treated with anthracycline-based chemotherapy within a randomized trial. Immunohistochemistry was performed on serial 2. High vs.

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